Medical Scientist Training Program > Program Program > Faculty Michael Gale, Jr., Ph.D. Michael Gale, Jr., PhD, is a Professor in the Department of Immunology at The University of Washington, School of Medicine. AU - Diamond, Michael S. AU - Gale, Michael. The nonprofit group EcoHealth Alliance received federal funding for its research without undergoing an independent review by the … Modern Virology Assays for Antiviral Drug Discovery, Vaccine Development and Pathogenesis Investigation. Vincent Racaniello Vincent, Alan ... Vincent Racaniello Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses. by Brenda L. Fredericksen and Brian C. Keller and Jamie Fornek and Michael G. Katze and Michael Gale Jr Journal of Virology, ISSN 0022-538X, 01/2008, Volume 82, Issue 2, pp. Arbovirologist, professor, and lab director at GWU who identifies defenses against emerging disease threats. Biosafety in Microbiological and Biomedical Laboratories. Pan et al. Author Summary Hepatitis C virus (HCV) is a positive-strand RNA virus and it is a major cause of liver disease worldwide affecting more than 170 million individuals. Dr. Apetrei studied medicine at the University of Iași, Romania. (2020) provide an overview of the current state of the art in electroactive triboelectric and piezoelectric devices as self-powered sensors and energy harvesters for soft robots and machines; bioinspired and hybrid approaches are also discussed. Virology publishes papers that provide advances to the understanding of virus biology. While a student at Purdue, Matt worked under Dr. Laszlo Csonka studying mechanisms of osmoregulation of the proU promoter in Salmonella Typhimurium.Matt arrived at Duke in the fall 2016 and started in the Horner lab the following spring. Thank you for your patience and understanding during … Rights and Permissions. Was there science behind the idea for the TV show Friends? He received his medical degree from Harvard Medical School and has been in practice for more than 20 years. Michael Gale Jr. et al. Michael Gale, Eileen M. Foy. RIG-I Signaling Is Essential For Influenza B Virus-Induced Rapid Interferon Gene Expression Sanna M. Mäkelä, Pamela Österlund, Veera Westenius, Sinikka Latvala, Michael S. Diamond, Michael Gale Jr., and Ilkka Julkunen J. Virol. As most microbial pathogens contain DNA and/or RNA during their life cycle, nucleic acid sensing has evolved as an essential strategy for host innate immune defense. Coverage of basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology help you master the essentials. Research and training are largely focused in the areas of immunology, virology, and microbial interactions, but the questions and strategies are broadly based in molecular biology, cell biology, biochemistry, genetics and genomics. Anastasia Gorelova. Targeting innate RNA sensors to the endomembrane system may enhance their … ... Matthew J. Thomas & Michael Gale … Hantaviruses replicate in human endothelial cells and accomplish this by restricting the early induction of beta interferon (IFN-β)- and IFN-stimulated genes (ISGs). ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology. Coronavirus disease 2019 (COVID-19), the highly contagious infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a catastrophic effect on the world’s demographics resulting in more than 2.9 million deaths worldwide, emerging as the most consequential global health crisis since the era of the influenza pandemic of 1918. Episode 85: Hepatitis C virus with Professor Michael Gale ... -c-virus-with-professor-michael-gale/ Vincent Racaniello: Today, we have a special TWiV. CiteScore values are based on citation counts in a range of four years (e.g. Joseph Galley. Steve Reed is the co-founder, President, and CEO of HDT Bio, based in Seattle, USA. Michael Katze is an American microbiologist. He has studied the virology and viral immunology of herpes viruses, retroviruses, including HIV and SIV, influenza virus, hepatitis C virus, and West Nile virus. DVM, MPH, PhD Assistant Professor. ... Journal of virology 82 (1), 335-345, 2008. Your account has been temporarily locked. ... Journal of virology 86 (17), 8937-8948, 2012. The virus has spread across the country and infected more than 2,100 U.S. residents 180 in Texas this year alone, so we have to learn how to deal with it," said Dr. Michael Gale, associate professor of microbiology at UT Southwestern and director of the study. Nicholas Wade, a retired New York Times science editor, slammed mainstream media on Sunday for failing to investigate a possible link between a Wuhan lab and the coronavirus outbreak. West Nile virus (WNV) is a RNA virus of the family Flaviviridae and the leading cause of mosquito-borne encephalitis in the United States. Cristian Cilloniz, Mary J Pantin-Jackwood, Chester Ni, Victoria S Carter, Marcus J Korth, David E Swayne, Terrence M Tumpey, and Michael G Katze J. Virol. Three researchers from China's Wuhan Institute of Virology became sick in November 2019 and ended up needing hospital care. This relationship has imposed numerous challenges on both the infecting virus and the host cell. 1/13-present (Editor since 4/02). Importantly, viruses must compete with the endogenous transcripts of the host cell for the translation of viral mRNA. . Virology, Nebraska Center for Virology Papers. Cho H, Proll SC, Szretter KJ, Katze MG, Gale M Jr, Diamond MS. Dr. Apetrei’s research focuses on simian immunodeficiency virus diversity and pathogenesis in natural hosts and upon cross-species transmission. Building on her interest of virus/host interactions, Dr. Horner joined the laboratory of Dr. Michael Gale Jr. at the University of Washington for her postdoctoral training in 2007. 12, Issue 555, eabc9396 DOI: 10.1126/scitranslmed.abc9396 AU - Polyak, Stephen J. PY - 2014/2. Dr. Michael S. Diamond is an infectious disease specialist in Saint Louis, Missouri. Episode #121 of the podcast This Week in Virology is a conversation about careers in virology, systems biology, innate immunity, and antiviral research recorded at the University of Washington in Seattle. O’Connor MA, Tisoncik-Go J, Lewis TB, Miller CJ, Bratt D, Moats CR, Smedley J, Klatt NR, Gale Jr, M, Fuller DH (2018). Arbovirology. Here, we examined how this outcome is achieved by comparing a natural SIV host, African green monkey (AGM) to an AIDS susceptible species, rhesus macaque (RM). Michael Lesher is an author, poet and lawyer whose legal work is mostly dedicated to issues connected with domestic abuse and child sexual abuse. West Nile virus (WNV) is a single-stranded RNA virus that causes West Nile fever.It is a member of the family Flaviviridae, specifically from the genus Flavivirus, which also contains the Zika virus, dengue virus, and yellow fever virus. The Department of Microbiology and Immunology at UNC – Chapel Hill represents a dynamic and exciting blend of disciplines and technology. 25 HIV and HCV co‐infection in hepatocytes and stellate cells reveals cooperative transcriptional activation between viruses and cell types Shadi Salloum 1, Cynthia Brisac 1, Rohit Jindal 2, Shyam Sundhar Bale 2, Nadia Alatrakchi 1, Annie Kruger 1, Anna Lidofsky 1, Martin L. Yarmush 2, Raymond T. Chung 1; 1 GI, MGH, Boston, MA; 2 Cen‐ter for Engineering in Medicine, Shriner, Boston, MA Sharie Keanne Ganchua. Michael Gale Jr 1 , Eileen M Foy Affiliation 1 Department of Microbiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9048, USA michael.gale@utsouthwestern.edu via Duke Health & News DURHAM, N.C. – The Duke Human Vaccine Institute has been awarded a contract in the amount of $28.1 million from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to house a virology quality assurance program for laboratories involved in HIV research. Michael Gale, Jr. University of Washinton. I’m speaking with Professor Michael Gale about Hepatitis C virus. Chris Mores, ScD. Dengue fever is the commonest viral haemorrhagic fever worldwide and is a leading cause of morbidity and mortality in the tropics. Zika viral persistence and tissue tropism in pigtail macaques is driven by early cellular innate immune responses. ... Rahe M, Gale m, Yuan J, and Kirkegaard K. 2013. complete, timely and most of all, easy to use. His academic appointments include Adjunct Professor of Medicine at Cornell University Medical College Research Professor of Pathobiology at the University of Washington. ... Virology. CiteScore: 5.2 ℹ CiteScore: 2020: 5.2 CiteScore measures the average citations received per peer-reviewed document published in this title. ... Virology. Your account has been temporarily locked due to incorrect sign in attempts and will be automatically unlocked in 30 mins. He then specialized in infectious diseases, before pursuing a Ph.D. in virology. Our team includes Belinda Heynes, Michael Gale, David Evans, and Chris Mores. 14, pp. PDF. Natural hosts of simian immunodeficiency virus (SIV) avoid AIDS despite lifelong infection. Esther Francisco, Mehul S. Suthar, Michael Gale, Amy B. Rosenfeld, Vincent R. Racaniello> ;Virology. Associate Editor, PLoS Pathogens, 1/09-present. On episode 85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses. Abbreviation of Virology. HIV, evolution of innate immunity to primate lentiviruses, virus adaptation to new. For the third year in a row, Dr. Michael Gale Jr. remains one of the most highly cited researchers in the world. LGP2, a member of the RIG-I-like receptor family, lacks the amino-terminal caspase activation recruitment domains (CARDs) required for initiating the activation of interferon regulatory factor 3 (IRF3) and interferon (IFN) transcription. Type I interferons (IFN-α/β) control viral infection by triggering the expression of genes that restrict transcription, translation, replication, and assembly. innate immunity virology infectious disease immunology systems biology. Qingsheng Li, Wuxun Lu & Jianshui Zhang. Jounral of Virology. … Authors: Neufeldt CJ, Joyce MA, VanBuren N, Kierkegaard K, Levin A, Gale Michael Jr., Tyrrell DLJ, and Wozniak RW. Kristina Chang's 3 research works with 76 citations and 226 reads, including: Vpu-Deficient HIV Strains Stimulate Innate Immune Signaling Responses in Target Cells Y1 - 2014/2. However, most positive-strand RNA viruses replicate within a modified organelle co-opted from intracellular membranes of the endomembrane system, which shields viral products from host cell innate immune sensors. PDF. Charles Murry, joint professor of pathology, cardiology, and bioengineering and director, ISCRM: The Murry laboratory is leading a collaborative effort with ISCRM investigators and the virology laboratory of Dr. Michael Gale to test whether human heart, kidney and brain organoids can be infected with the SARS-CoV-2 virus. Michael Gale Jr. will never forget the sound his ‘68 Mustang made when its engine roared back to life in 1993. Dr. Michael Gale, Jr. received his training at the University of Washington School of Public Health and Community Medicine. The broad spectrum of ARB anti-viral activity led us to evaluate its effect on hepatitis C virus (HCV) infection and replication in cell culture. Tagged as: antiviral, hcv, hepatitis, hepatitis C virus, hepatocellular carcinoma, liver cancer, michael gale, viral, virology, virus Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses. McGill's Medical Guide Includes causes, symptoms, and treatments of illnesses caused by bacteria and viruses. Nature Medicine. He served on the faculty of the University of Texas Southwestern Medical Center until joining the University of Washington in 2007. Some critics found fault with the book's emphasis on the experiences … In a series of experiments, members of Greninger’s lab worked with the lab of Michael Gale, Jr., University of Washington School of Medicine professor of immunology and director of the Center for Innate Immunity and Immune Disease. The virus has spread across the country and infected more than 2,100 U.S. residents – 180 in Texas this year alone, so we have to learn how to deal with it," said Dr. Michael Gale, associate professor of microbiology at UT Southwestern and director of the study. Virology. The author "does a great public service by providing easily comprehensible digests of hard research on virology and immunology, past and present," observed Nation contributor Joe Knowles. It is the standardised abbreviation to be used for abstracting, indexing and referencing purposes and meets all criteria of the ISO 4 standard for abbreviating names of scientific journals. Professor, Department of Immunology ... most notably the Washington National Primate Center’s Virology Core (primarily HIV research), and the University of Washington School of Nursing’s Sleep Medicine Department. Activation of the innate immune response is important for controlling early virus replication and spread. Her goal, as always, is to save the world. University of Washington. He was an international leader in the application of genome sequencing, animal models, and systems biology approaches to virology and immunology.Katze was formerly Professor of Microbiology at the … AU - Liang, T. Jake. The Infectious Disease & Translational Medicine Division is comprised of three Resource Cores: Virology & Immunology Core (V&IC), the High Throughput Molecular Profiling Core, and the Computer Data Analysis Core. Nature Communications: 3371; doi: 10.1038/s41467-018-05826-w, PMID: 30135445 Microbial infections are recognized by the innate immune system through germline-encoded pattern recognition receptors (PRRs). The lab uses molecular, biochemical, and functional genomics approaches to study SARS-CoV-2, HIV, Zika virus, West Nile virus, Hanta virus, influenza A virus, and other emerging and re-emerging viruses. The HCV plenary was presented by Associate Professor Michael Gale Jr., University of Washington, USA on ‘Mechanisms of nonself recognition of hepatitis C virus and immune signalling regulation of HCV infection’. Virology, Nebraska Center for Virology Papers. Michael Gale, Jr., PhD (University of Washington) “Innate Immune Control and Chronic Viral Infection” Sponsored by the Duke Center for Virology, Duke Comprehensive Cancer Center, Duke Center for AIDS Research, and GlaxoSmithKline . … Since then, my interest turned to viruses: This tiny little piece of genetic material can kill you.” Allan Hoffman, bioengineering “I built the program called biomaterials here. PLos Pathogens. D., Professor of Immunology at the University Of Washington School Of Medicine. A board created to oversee research that could make dangerous pathogens more contagious did not review a National Institutes of Health grant that funded a project in Wuhan, China to genetically modify bat-based coronaviruses, according to a new report. Dr. Gale is an expert in innate immunity, virology, immunology, cytokine biology, virus/host interactions, and immune signaling. In the past few years, Nexcelom Bioscience has worked with leading labs in the field of virology from government agencies, academic labs, and pharmaceutical companies such as the Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and National Institute … Virologist, professor, and research administrator at the Li Ka Shing Institute of Virology. Dear Colleagues, It is with great pleasure that we announce the conference Viruses 2020 - Novel Concepts in Virology to be held in Barcelona, Spain, 5-7 February 2020. Grim public health statistics highlight the need for vaccines that can rapidly confer protection after a single dose and be manufactured using components suitable for scale-up and efficient distribution. Fredericksen, BL, Smith, M, Katze, MG, Shi, PY & Gale, M 2004, ' The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway ', Journal of virology, vol. The Administrative Core is designed to facilitate communication, planning, data sharing, and scientific and fiscal oversight of the component research projects of the Program. Sort. Title. The ongoing COVID-19 pandemic, caused by infection with SARS-CoV-2, is having a dramatic and deleterious impact on health services and the global economy. Usefulness of Real-time Reverse Transcription Polymerase Chain Reaction Technique as an animal disease diagnostic-review. Deborah Fuller. Infection of cells with HCV leads to rearrangement of cytoplasmic host cell membranes and the formation of the membranous web (MW) containing viral replication and assembly complexes. A handoff is defined as the transfer of role and responsibility from one person to another in a physical or mental process. 2012 Mar 86(5) 2437-46 Similar articles in PubMed DOI: 10.1128/JVI.06156-11 Yueh-Ming Loo, Michael Gale Jr. PMID: 17230179 DOI: 10.1038/445267a No abstract available. jcg59@pitt.edu Interdisciplinary Biomedical Graduate Program (IBGP) ... Michael Whaby. Follow. Loop enables you to stay up-to-date with the latest discoveries and news, connect with researchers and form new collaborations. Arbidol (ARB) is an antiviral compound that was originally proven effective for treatment of influenza and several other respiratory viral infections. Science Translational Medicine 05 Aug 2020: Vol. Hosts: Vincent Racaniello, Michael Katze, Michael Gale, Deborah Fuller, and Shawn Iadonato. Michael Gale, Jr. University of Washinton Verified email at uw.edu. Yueh Ming Loo, Jamie Fornek, Nanette Crochet, Gagan Bajwa, Olivia Perwitasari, Luis Martinez-Sobrido, Shizuo Akira, Michelle A. Gill, Adolfo García-Sastre, Michael G. Katze, Michael Gale Int Med - … Follow. scg40@pitt.edu Molecular Virology and Microbiology. Collaborators on the Training Grant: Michael Gale, Jennifer Hyde, Martin Prlic, Joshua Woodward Jason Smith The Smith lab studies mucosal immunity to viral infection, with a particular emphasis on the role of enteric alphadefensin antimicrobial peptides in the pathogenesis of gastrointestinal infections. (2005) Nature 436: 939-940) Highly visible handoffs, such as those that take place in sports, typically involve precision and risk. Michael Gale, immunology and virology “I got interested in infectious disease because my sister got hepatitis A virus. Caister Academic Press (2010). ang123@pitt.edu Molecular Pharmacology. Vincent Racaniello vrr1@columbia.edu virus, virology, microbiology, infection, twiv no. ... Katharina Esser-Nobis, Michael Gale Jr, Steven Shen, Ryan A Langlois. 2019 Feb 1 3 citations IRF5 regulates unique subset of genes in dendritic cells during West Nile virus infection. The MW is thought to function in … The ISO4 abbreviation of Virology is Virology . He served on the faculty of the University of Texas Southwestern Medical Center until joining the University of Washington in 2007. Source for information on The Discovery of Viruses: Science and Its Times: Understanding the Social Significance of Scientific Discovery dictionary. Michael Rahe. We are a network of labs focused in virology, photochemistry, and epidemiology. The on-the-ground team for the CATCH study, which sought to find undiagnosed HIV+ children. Through these cores, the division supports the following programs: Core Research Program, Affiliate Research Program and Training Program. R. Manojkumar, A. Sanyal, D. Hemadri (2006). Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Sort by citations Sort by year Sort by title. Photo courtesy of Global Center for Integrated Health of Women, Adolescents, and Children (Global WACh). The CIIID is directed by Michael Gale, Jr. Ph. Rights and Permissions. In non-infected cells RIG-I is found in a resting state with the RD covering the RNA-binding and helicase domains (Saito et al., 2007).CARDs of ‘resting’ RIG-I are also folded over one another with these interactions governing the signaling activity of RIG-I (Fig. Today, the most common way people get infected is by needle sharing during intravenous drug use. Jump to: 2021 PDF. Jeremy Gale. He served on the faculty of the University of Texas Southwestern Medical Center until joining the University of Washington in 2007. The car was given to him in 1977 by his father. Zika virus (ZIKV) is a flavivirus that has recently emerged from Uganda, into Asia, across the Pacific and now into the Americas. We have been publishing the results of basic research in all branches of virology for over 60 years. Jump to: 2021 PDF. jtg43@pitt.edu Biomedical Masters Program. Professor, Department of Immunology Adjunct Professor, Dept. He has studied the virology and viral immunology of herpes viruses, retroviruses, including HIV and SIV, influenza virus, hepatitis C virus, and West Nile virus. Matthew Sacco, BS – Graduate Student (MGM) Matt was born and raised in Connecticut and received his BS in Microbiology and Genetics from Purdue University. Michael Scott Boyce’s profile, publications, research topics, and co-authors
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